HR+/HER2- 型晚期乳癌治療新喜訊！

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醫療新知 > HR+/HER2- 型晚期乳癌治療新喜訊！

HR+/HER2- 型晚期乳癌治療新喜訊！

06-02-2023

CDK4/6抑製劑的出現改變了荷爾蒙受體陽性、第二型人類表皮生長因子受體陰性(HR+/HER2-)晚期乳癌治療的格局，並成為標準內分泌聯合治療方案重要元素，但是對於疾病進展快、腫瘤較大、徵狀嚴重的惡性乳癌患者，化療仍是標準的治療選擇。與單藥化療相比，聯合化療具有更高的客觀緩解率(Overall Response Rate, ORR)和更長的無惡化存活期(Progression-Free Survival, PFS)，成為這些患者之傳統首選治療方案。

在 2022年12月的世界性乳癌醫學會議SABCS 中，台灣乳癌權威盧彥伸教授公佈第二期臨床試驗RIGHT Choice的結果。RIGHT Choice是首個針對轉移性HR+/HER2- 惡性乳腺癌患者使用聯合化療對比荷爾蒙療法聯合CDK4/6抑制劑的第二期臨床隨機對照試驗。為這類患者帶來化療以外之選擇。

此資訊由諾華製藥（香港）有限公司全力支持
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