{"id":415,"date":"2021-07-28T09:00:11","date_gmt":"2021-07-28T01:00:11","guid":{"rendered":"https:\/\/cancerinformation.com.hk\/BreatheWithMe\/?p=415"},"modified":"2021-07-28T04:41:40","modified_gmt":"2021-07-27T20:41:40","slug":"%e6%af%94%e7%ac%ac%e4%b8%80%e4%bb%a3%e6%9b%b4%e5%bc%b7%e6%95%88%e7%9a%84egfr%e8%82%ba%e7%99%8c%e6%a8%99%e9%9d%b6%e8%97%a5%e8%83%bd%e9%a1%af%e8%91%97%e5%bb%b6%e9%95%b7%e6%82%a3%e8%80%85%e5%ad%98","status":"publish","type":"post","link":"https:\/\/cancerinformation.com.hk\/BreatheWithMe\/%e6%af%94%e7%ac%ac%e4%b8%80%e4%bb%a3%e6%9b%b4%e5%bc%b7%e6%95%88%e7%9a%84egfr%e8%82%ba%e7%99%8c%e6%a8%99%e9%9d%b6%e8%97%a5%e8%83%bd%e9%a1%af%e8%91%97%e5%bb%b6%e9%95%b7%e6%82%a3%e8%80%85%e5%ad%98\/","title":{"rendered":"\u6bd4\u7b2c\u4e00\u4ee3\u66f4\u5f37\u6548\u7684EGFR\u80ba\u764c\u6a19\u9776\u85e5\u80fd\u986f\u8457\u5ef6\u9577\u60a3\u8005\u5b58\u6d3b\u671f"},"content":{"rendered":"

\u300c\u6211\u5f9e\u4e0d\u5438\u7159\uff0c\u70ba\u751a\u9ebc\u80ba\u764c\u6703\u627e\u4e0a\u6211\uff1f\u300d\u4e0d\u5c11\u975e\u5438\u7159\u80ba\u764c\u60a3\u8005\u5728\u78ba\u8a3a\u7684\u4e00\u523b\u90fd\u6709\u9019\u6a23\u7684\u7591\u554f\u3002\u7684\u78ba\uff0c\u73fe\u4eca\u6108\u4f86\u6108\u591a\u975e\u5438\u7159\u8005\u60a3\u4e0a\u80ba\u764c\uff0c\u539f\u56e0\u6216\u8207\u63a5\u89f8\u4e8c\u624b\u7159\uff0c\u751a\u81f3\u4e09\u624b\u7159\u6709\u95dc\u3002\u6b64\u5916\uff0c\u65e5\u8da8\u56b4\u91cd\u7684\u7a7a\u6c23\u6c61\u67d3\u554f\u984c\uff0c\u4ee5\u53ca\u7531\u907a\u50b3\u5f15\u8d77\u7684\u56e0\u7d20\uff0c\u90fd\u662f\u8a98\u767c\u80ba\u764c\u7684\u98a8\u96aa\u3002\u6709\u7814\u7a76\u4ea6\u767c\u73fe\uff0c\u975e\u5438\u7159\u7684\u80ba\u764c\u60a3\u8005\u4ee5\u5e74\u8f15\u5973\u6027\u504f\u591a\uff0c\u7576\u4e2d\u4e0d\u5c11\u60a3\u8005\u5e36\u6709EGFR\u57fa\u56e0\u7a81\u8b8a\u3002\u81e8\u5e8a\u816b\u7624\u79d1\u5c08\u79d1\u91ab\u751f\u5433\u96f2\u82f1\u6307\u51fa\uff0c\u5728\u975e\u5c0f\u7d30\u80de\u80ba\u764c\uff08NSCLC\uff09\u4e2d\uff0c\u300c\u8868\u76ae\u751f\u9577\u56e0\u5b50\u53d7\u9ad4\u300d\uff08EGFR\uff09\u662f\u6700\u5e38\u898b\u7684\u57fa\u56e0\u7a81\u8b8a\u985e\u578b\uff0c\u7279\u5225\u662f\u5728\u4e9e\u6d32\uff0c\u4f54\u6240\u6709NSCLC\u500b\u6848\u7d04\u516d\u81f3\u4e03\u6210\uff0c\u9060\u6bd4\u6b50\u6d32\u570b\u5bb6\u7684\u5169\u6210\u70ba\u9ad8\u3002<\/p>\n

\u7b2c\u4e8c\u3001\u4e09\u4ee3\u7684<\/b><\/strong>EGFR<\/b><\/strong>\u6291\u5236\u5291\u5ef6\u9577\u60a3\u8005\u5b58\u6d3b\u7387<\/b><\/strong><\/span><\/h5>\n

EGFR\u57fa\u56e0\u7a81\u8b8a\u6703\u9a45\u4f7f\u7d30\u80de\u6301\u7e8c\u767c\u51fa\u751f\u9577\u8a0a\u865f\uff0c\u4ee4\u7d30\u80de\u4e0d\u53d7\u63a7\u5236\u5730\u751f\u9577\uff0c\u5f62\u6210\u764c\u75c7\u3002EGFR\u57fa\u56e0\u7a81\u8b8a\u578b\u80ba\u764c\u4e2d\u6700\u5e38\u898b\u7684\u662f\u7b2c19\u865f\u5916\u986f\u5b50\uff08exon 19\uff09\u7f3a\u5931\u548c\u7b2c21\u865f\u5916\u986f\u5b50\uff08exon 21\uff09L858R\u7a81\u8b8a\uff0c\u5b83\u5011\u5206\u5225\u4f54\u6574\u9ad4EGFR\u57fa\u56e0\u7a81\u8b8a\u578b\u80ba\u764c\u768446%\u53ca38%\u3002\u91dd\u5c0dEGFR\u57fa\u56e0\u7a81\u8b8a\u578b\u80ba\u764c\uff0c\u76ee\u524d\u7684\u9996\u9078\u6cbb\u7642\u65b9\u6848\u70ba\u6a19\u9776\u85e5\u7269\u300cEGFR\u6291\u5236\u5291\u300d\uff0c\u900f\u904e\u963b\u65b7\u764c\u7d30\u80de\u751f\u9577\u8a0a\u606f\u7684\u50b3\u905e\uff0c\u5f9e\u800c\u63a7\u5236\u816b\u7624\u3002\u5433\u91ab\u751f\u8868\u793a\uff1a\u300c\u73fe\u6642\u7b2c\u4e00\u7dda\u6cbb\u7642\u85e5\u7269\u9078\u64c7\u5305\u62ec\u7b2c\u4e00\u3001\u7b2c\u4e8c\u548c\u7b2c\u4e09\u4ee3\u7684EGFR\u6291\u5236\u5291\u3002\u7b2c\u4e8c\u548c\u7b2c\u4e09\u4ee3\u7684EGFR\u6291\u5236\u5291\u6bd4\u7b2c\u4e00\u4ee3\u6548\u7528\u66f4\u5f37\uff0c\u80fd\u6709\u6548\u5ef6\u9577\u60a3\u8005\u5b58\u6d3b\u7387\u548c\u816b\u7624\u53d7\u63a7\u7684\u6642\u9593\u3002\u4ee5\u5f80\uff0c\u4f7f\u7528\u7b2c\u4e00\u4ee3EGFR\u6291\u5236\u5291\u7684\u60a3\u8005\uff0c\u5b58\u6d3b\u671f\u4e2d\u4f4d\u6578\u7d04\u70ba27\u500b\u6708\uff0c\u800c\u7b2c\u4e8c\u53ca\u7b2c\u4e09\u4ee3EGFR\u6291\u5236\u5291\u5247\u5c07\u5b58\u6d3b\u671f\u4e2d\u4f4d\u6578\u5ef6\u9577\u81f334\u81f339\u500b\u6708\u3002\u5176\u4e2d\u7b2c\u4e8c\u4ee3EGFR\u6291\u5236\u5291\u91dd\u5c0dexon 19 deletions\u4ee5\u53caexon 21 L858R\u7a81\u8b8a\u76f8\u7576\u6709\u6548\uff0c\u7121\u60e1\u5316\u5b58\u6d3b\u671f\u4e2d\u4f4d\u6578\u5206\u5225\u9054\u523016.5\u500b\u6708\u548c12.3\u500b\u6708\uff0c\u53cd\u89c0\u7b2c\u4e00\u4ee3EGFR\u6291\u5236\u5291\u53ea\u80fd\u9054\u52309\u81f310\u500b\u6708\u3002\u300d<\/p>\n

\u9078\u64c7EGFR\u6291\u5236\u5291\u7684\u8003\u616e\u56e0\u7d20<\/strong><\/span><\/h5>\n

\u5982\u4e0a\u6587\u6240\u8a00\uff0c\u76ee\u524d\u5e02\u9762\u4e0a\u5df2\u6709\u5e7e\u6b3e\u00a0EGFR\u6291\u5236\u5291\u88ab\u6838\u51c6\u61c9\u7528\u65bcEGFR\u57fa\u56e0\u7a81\u8b8a\u578b\u975e\u5c0f\u7d30\u80de\u80ba\u764c\u7684\u7b2c\u4e00\u7dda\u6cbb\u7642\u85e5\u7269\uff0c\u5b83\u5011\u7684\u6548\u679c\u90fd\u975e\u5e38\u986f\u8457\u3002\u5433\u91ab\u751f\u89e3\u91cb\uff0c\u91ab\u751f\u6703\u6839\u64da\u60a3\u8005\u7684\u7a81\u8b8a\u7a2e\u985e\uff0c\u4f8b\u5982exon 19\/21\u3001\u6709\u6c92\u6709\u51fa\u73feT790M\u7a81\u8b8a\uff0c\u4ee5\u53ca\u56e0\u61c9\u816b\u7624\u64f4\u6563\u7bc4\u570d\u548c\u60a3\u8005\u7684\u8eab\u9ad4\u72c0\u6cc1\u7b49\uff0c\u4f86\u70ba\u60a3\u8005\u9078\u64c7\u6700\u5408\u9069\u7684\u85e5\u7269\u3002<\/p>\n

EGFR\u6291\u5236\u5291\u7684\u526f\u4f5c\u7528\u666e\u904d\u5c6c\u65bc\u8f15\u5fae\u4e14\u80fd\u6709\u6548\u4e88\u4ee5\u63a7\u5236\uff0c\u6700\u5e38\u898b\u7684\u526f\u4f5c\u7528\u70ba\u76ae\u75b9\u3001\u76ae\u819a\u4e7e\u71e5\u3001\u75b2\u5026\u548c\u8179\u7009\u7b49\u3002\u7136\u800c\uff0c\u5433\u91ab\u751f\u63d0\u9192\uff0c\u500b\u5225\u60a3\u8005\u6216\u6703\u51fa\u73fe\u7f55\u898b\u800c\u56b4\u91cd\u7684\u4f75\u767c\u6027\uff0c\u4f8b\u5982\u85e5\u7269\u5f15\u8d77\u7684\u80ba\u708e\u3002\u56e0\u6b64\uff0c\u5018\u60a3\u8005\u670d\u85e5\u5f8c\u611f\u5230\u4efb\u4f55\u4e0d\u9069\uff0c\u61c9\u8fc5\u901f\u6c42\u91ab\u3002<\/p>\n

\u5433\u91ab\u751f\u7684\u8a71<\/b><\/strong>\u2026\u2026<\/b><\/strong><\/span><\/h5>\n

\u300c\u4e0d\u5c11\u60a3\u8005\u5728\u78ba\u8a3a\u7b2c\u56db\u671f\u80ba\u764c\u6642\u90fd\u6703\u611f\u5230\u7d55\u671b\u3002\u5176\u5be6\uff0c\u96a8\u8457\u91ab\u85e5\u767c\u5c55\u7684\u9032\u6b65\uff0c\u85e5\u7269\u63a8\u9673\u51fa\u65b0\uff0c\u5373\u4f7f\u662f\u7b2c\u56db\u671f\u80ba\u764c\uff0c\u4e5f\u6709\u5f88\u591a\u6709\u6548\u7684\u6cbb\u7642\u9078\u64c7\uff0c\u60a3\u8005\u7684\u5b58\u6d3b\u671f\u4e5f\u6bd4\u4ee5\u5f80\u986f\u8457\u5ef6\u9577\uff0c\u540c\u6642\u5f97\u4ee5\u4fdd\u6301\u4e00\u5b9a\u7684\u751f\u6d3b\u8cea\u7d20\u3002\u6211\u5e0c\u671b\u5927\u5bb6\u4e0d\u8981\u6c23\u9912\uff0c\u6b63\u9762\u6a02\u89c0\u7684\u5fc3\u614b\u662f\u4e00\u5e16\u826f\u85e5\uff0c\u52a0\u4e0a\u9078\u7528\u6700\u5408\u9069\u7684\u85e5\u7269\uff0c\u96d9\u7ba1\u9f4a\u4e0b\uff0c\u80ba\u764c\u4fbf\u4e0d\u518d\u53ef\u6015\uff01\u300d<\/p>\n

 <\/p>\n

\"\"\u00a0<\/b><\/strong><\/p>\n

\u5433\u96f2\u82f1\u91ab\u751f<\/b><\/strong><\/p>\n

\u81e8\u5e8a\u816b\u7624\u79d1\u5c08\u79d1\u91ab\u751f<\/b><\/strong><\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

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